What question did this study set out to answer?

This study aims to examine the relationship between hemoglobin A1c levels, cardiovascular disease, and total mortality in adults.

September 21, 2004Annals of Internal Medicine

Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk

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This study aims to examine the relationship between hemoglobin A1c levels, cardiovascular disease, and total mortality in adults.
Prospective population study involving 4662 men and 5570 women aged 45 to 79 in Norfolk.
Assessments of hemoglobin A1c and cardiovascular disease risk factors conducted from 1995 to 1997.
Follow-up to 2003 for cardiovascular disease events and mortality assessments.
Higher hemoglobin A1c levels correlated with increased cardiovascular disease (806 events) and all-cause mortality (521 deaths).
Increased hemoglobin A1c by 1 percentage point was associated with a relative risk for death of 1.24 for men and 1.28 for women (both P < 0.001).
Majority of deaths occurred in individuals with hemoglobin A1c between 5% and 6.9%, indicating moderate elevation poses significant risk.

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Implication

Prospective population study examines hemoglobin A1c's impact on cardiovascular disease and mortality risk in adults, suggesting a continuous relationship.

Cite This Study

Khaw et al. (2004) studied this question.

synapsesocial.com/papers/6a07f8e809b3c82015378e22 https://doi.org/10.7326/0003-4819-141-6-200409210-00006

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Implication

Prospective population study examines hemoglobin A1c's impact on cardiovascular disease and mortality risk in adults, suggesting a continuous relationship.

Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk

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Discussion

Implication

Cite This Study

Association of Hemoglobin A1c with Cardiovascular Disease and Mortality in Adults: The European Prospective Investigation into Cancer in Norfolk

Key Points

Discussion

Implication

Cite This Study

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