Key result
Hyperinsulinemia in older hypertensive subjects was associated with increased left ventricular mass (P<.05) and better systolic function (P<.0001) compared to those with lower insulin levels.
Why the study?
Does hyperinsulinemia affect left ventricular structure and function in older hypertensive subjects?
Population
37 hypertensive subjects (17 men/20 women) aged 50 to 80
Comparison
Hyperinsulinemia vs Normoinsulinemia
Design
Cross-sectional
Authors
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Does not support practice change in older hypertensives; leaves open causal role of hyperinsulinemia in LV remodeling.
Cross-Sectional (n=37)
Does hyperinsulinemia affect left ventricular structure and function in older hypertensive subjects?
p-value: p=<.05
In older hypertensive subjects, hyperinsulinemia is associated with increased left ventricular mass and wall thickness, alongside better systolic performance.
Scuteri et al. (1999) conducted a cross-sectional in Hypertension (n=37). Hyperinsulinemia vs. Lower insulin levels (below median) was evaluated on Left ventricular mass and systolic function (p=<.05). Hyperinsulinemia in older hypertensive subjects was associated with increased left ventricular mass (P<.05) and better systolic function (P<.0001) compared to those with lower insulin levels.
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