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May 16, 2026Next research.Open Access

Mark Your Targets: Nanoparticles for Atherosclerosis

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Authors

YSYannis V. SimosKSKonstantinos SpyridisKSKonstantinos Spyrou

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Overview

Randomized trial shows nanoparticle effectiveness in targeting atherosclerotic plaques, suggesting improved treatment strategies.

Key Points

  • This research aims to explore the use of nanoparticles for molecular targeting and therapy in atherosclerosis.
  • Engineered nanoparticles were used to target specific markers on endothelial cells, macrophages, and foam cells.
  • Theranostic nanoparticles were integrated for imaging and drug delivery at atherosclerotic sites.
  • Advanced imaging modalities and computational models provided insights into plaque vulnerability.
  • Nanoparticles effectively localized to targeted atherosclerotic plaques, facilitating drug delivery.
  • Improved imaging of vulnerable plaques was achieved using the nanotechnological approach.
  • The integration of AI-assisted models demonstrated enhanced personalized treatment planning.

Cite This Study

Simos et al. (2026) studied this question.

synapsesocial.com/papers/6a0809bea487c87a6a40b950https://doi.org/10.1016/j.nexres.2026.101876
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