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October 13, 2022Frontiers in PharmacologyOpen Access

Targeted nanomedicine-based approaches present unique advantages over conventional techniques for the characterization and detection of atherosclerosis plaque vulnerability.

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Why the study?

Traditional imaging depends on luminal stenosis and underestimates non-stenotic high-risk plaque, leaving the identification of vulnerable atherosclerotic plaques limited.

Design

Review

Authors

XLXue LiMWMenglin WuJLJiang Li

Discussion

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Overview

Should not yet change plaque imaging practice; leaves open targeted nanomedicine validation in prospective trials.

Structured PICO

I
Intervention
Targeted nanomedicine-based imaging techniques
C
Comparator
Traditional imaging techniques
O
Outcome
Characterization and detection of atherosclerosis plaque vulnerability

Targeted nanomedicines hold significant potential for improving the imaging and risk stratification of vulnerable atherosclerotic plaques compared to traditional luminal diameter quantification.

Cite This Study

Li et al. (2022) studied this question.

synapsesocial.com/papers/6a1bc2d401af05bf0da8eadchttps://doi.org/10.3389/fphar.2022.906512
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Also Consider

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  1. 1Advances of nanoparticle-mediated diagnostic and theranostic strategies for atherosclerosis2023 · 12 citations
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  4. 4Nanotechnology for Molecular Imaging of Atherosclerosis: Current Design and Approaches2021 · 2 citations
  5. 5Engineering Nanoplatforms for Theranostics of Atherosclerotic Plaques2024 · 19 citations