Key result
Self-management of oral anticoagulants using CoaguChek significantly increased the percentage of INR values within the target range compared to conventional management (72.9% vs 53.9%; p=0.01).
Why the study?
Does self-management of oral anticoagulants improve INR control and quality of life in patients who underwent elective mechanical aortic valve replacement?
Population
62 consecutive patients who underwent elective mechanical aortic valve replacement
Comparison
Self-management of oral anticoagulants using… vs Conventional management controlled by the Local…
Design
RCT, Randomized into two groups
Follow-up
1 year
Authors
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Supports self-management of anticoagulation after mechanical AVR; confirms benefits for INR control in this RCT.
RCT (n=62)
randomized
Does self-management of oral anticoagulants improve INR control and quality of life in patients who underwent elective mechanical aortic valve replacement?
Absolute Event Rate: 72.9% vs 53.9%
p-value: p=0.01
Self-management of oral anticoagulation significantly improves INR control and physical quality of life compared to conventional thrombosis service management in patients with mechanical aortic valves.
Hamad et al. (2008) conducted an RCT in elective mechanical aortic valve replacement (n=62). Self management using CoaguChek vs. Conventional management controlled by the Local Thrombosis Service was evaluated on Total number of international normalized ratio (INR) values within the target range (2.5-4.5) (p=0.01). Self-management of oral anticoagulants using CoaguChek significantly increased the percentage of INR values within the target range compared to conventional management (72.9% vs 53.9%; p=0.01).
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