Key result
Integrating molecular mechanisms with CMR imaging may improve customized management of postischemic adverse remodeling.
Why the study?
Despite reduced peri-acute myocardial infarction mortality with reperfusion therapy, new-onset heart failure has increased, and aggregating heart failure types has obscured the complex biology of postischemic remodeling.
A deeper understanding of the multifaceted mechanisms of postischemic cardiac remodeling and the use of cardiac magnetic resonance imaging may contribute to more customized patient management in heart failure.
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Hypothesis-generating for CMR-integrated management in post-MI remodeling; prospective trials needed before clinical adoption.
Gronda et al. (2019) conducted a review in Left ventricular postischemic remodeling and heart failure. Postischemic adverse cardiac remodeling involves complex molecular mechanisms, and understanding these factors alongside cardiac magnetic resonance imaging may improve customized patient management.
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