Research on gender differences in heart failure in Asia lags significantly behind Western countries, highlighting a critical knowledge gap in epidemiology, risk factors, therapy, and prognosis.
There is a critical knowledge gap regarding gender differences in heart failure in Asian populations compared to Western populations, highlighting the need for dedicated, high-quality clinical trials and cohorts in Asia.
Gender differences in heart failure (HF), ranging from epidemiological and pathophysiological factors to therapeutic response and prognosis, have been well documented in Western countries, especially in Europe and North America. The above gender differences in HF found in Westerners are rarely investigated in Asians. In this review, we explore the worrying knowledge gap on the gender differences in HF that existed in Asia in contrast with Western populations based on the following four aspects: epidemiology, risk factors, therapy, and prognosis. Finally, we conclude that investigations of gender differences in HF in Asia lag behind those in Europe and North America. Future work is required to establish and better use the high-level, population-based cohorts and develop our own high-quality, convincing clinical trials to deliver robust gender-specific conclusions in Asia.
Qiu et al. (Thu,) conducted a review in Heart failure. Research on gender differences in heart failure in Asia lags significantly behind Western countries, highlighting a critical knowledge gap in epidemiology, risk factors, therapy, and prognosis.