Key result
VA-ECMO normalizes EF within one week in a case of catecholamine-induced cardiomyopathy with cardiogenic shock.
Case Report (n=1)
No
VA-ECMO combined with alpha blockers and subsequent adrenalectomy successfully treated a case of severe catecholamine-induced cardiomyopathy secondary to pheochromocytoma.
A 55-year-old female patient was presented with severe dyspnea due to sudden onset of heart failure (ejection fraction (EF) <10%). Echocardiogram showed a takotsubo pattern with an akinetic apical segment. Coronary angiography did not reveal any obstructive disease. She became hypotensive which was refractory to conventional pressor agents. Catecholamine-induced cardiomyopathy was suspected after the CT scan of the abdomen showed a 4 cm necrotic right adrenal mass consistent with pheochromocytoma (PHEO). Venous arterial extracorporeal membrane oxygenation and α blockers were initiated. There was a rapid improvement in cardiac function with EF normalising in 1 week. Subsequently, β-blockers were added and right adrenalectomy was done 3 weeks after the admission. She did extremely well after surgery with her blood pressure normalising without the need for antihypertensive therapy. Genetic evaluation revealed no pathogenic mutations implicated in the development of PHEO.
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Garla et al. (2019) conducted a case report in Catecholamine-induced cardiomyopathy (n=1). Venous arterial extracorporeal membrane oxygenation (VAECMO) was evaluated on Ejection fraction (EF). In a 55-year-old female with catecholamine-induced cardiomyopathy and cardiogenic shock, treatment with venous arterial extracorporeal membrane oxygenation led to rapid normalization of ejection fraction within one week.
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