Key result
Deviations from normovolaemia significantly influence cardiovascular responses to orthostatic and environmental stress by restricting venous return and cardiac output.
This review proposes that normovolaemia can be functionally defined as the central blood volume at which the heart operates on the plateau of the Frank-Starling curve in the supine resting position, and discusses how deviations from this state influence cardiovascular responses to environmental stress.
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Alerts clinicians to volume status in stress testing; extends Frank-Starling insights but leaves open prospective validation.
Truijen et al. (2010) conducted a review in Cardiovascular control during orthostatic and environmental stress. Deviations from normovolaemia was evaluated. Deviations from normovolaemia significantly influence cardiovascular responses to orthostatic and environmental stress by restricting venous return and cardiac output.
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