Why the study?
To examine the association between syncope and all-cause mortality in patients with heart failure.
Does syncope increase all-cause mortality in patients with heart failure?
Population
Patients with HF identified from January 1, 2010, to December 31, 2015
Comparison
HF patients with syncope vs 1:1 propensity-matched HF patients without syncope
Design
Retrospective propensity score-matched cohort study
Key result
Syncope did not independently predict all-cause mortality in heart failure patients overall, but was a significant predictor in the subgroup with reduced EF and cardiac devices (P=0.038).
Authors
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Syncope should not yet inform mortality risk stratification in most heart failure patients; hypothesis-generating for prognostic value in HFrEF with devices.
Cohort
Does syncope increase all-cause mortality in patients with heart failure?
p-value: p==.038
Syncope is not an independent predictor of all-cause mortality in the general heart failure population, but it is a significant predictor in patients with HFrEF and cardiac implantable electronic devices.
Rattanawong et al. (2025) conducted a cohort in Heart failure. Syncope vs. Heart failure without syncope was evaluated on All-cause mortality (p==.038). Syncope did not independently predict all-cause mortality in heart failure patients overall, but was a significant predictor in the subgroup with reduced EF and cardiac devices (P=0.038).