Key result
Ambulatory PA pressure monitoring linked to ~55% fewer 90-day all-cause readmissions versus pre-implantation.
Why the study?
Following findings from the CHAMPION trial showing lower heart failure hospitalization rates with ambulatory pulmonary artery pressure monitoring, the authors investigated its effect on 90-day readmission rates after hospitalization.
Does ambulatory pulmonary artery pressure monitoring reduce 30-day and 90-day all-cause readmission rates in patients with heart failure?
Cohort (n=459)
Yes
Does ambulatory pulmonary artery pressure monitoring reduce 30-day and 90-day all-cause readmission rates in patients with heart failure?
Effect estimate: IRR 0.45 (95% CI 0.35-0.58)
p-value: p=< 0.0001
Ambulatory pulmonary artery pressure monitoring is associated with significantly lower 30-day and 90-day all-cause readmission rates in a real-world heart failure population.
May support PAP monitoring to lower post-HF readmissions; leaves open need for randomized confirmation.
AIMS: In the CHAMPION (CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in New York Heart Association Functional Class III Heart Failure Patients) trial, heart failure hospitalization (HFH) rates were lower in patients with ambulatory pulmonary artery pressure (PAP) monitoring guidance. We investigated the effect of ambulatory haemodynamic monitoring on 90 day readmission rates after HFH. METHODS AND RESULTS: We retrospectively analysed patients across the Advocate Aurora Health hospital network who had undergone PAP sensor implantation between 1 October 2015 and 31 October 2019. Patients with a ventricular assist device (VAD) or transplant prior to implantation were excluded. Rates of total HFH and 30 and 90 day all-cause readmission up to 12 months after implantation were collected, while censoring for an endpoint of heart transplantation, VAD, or death. Event rates were compared using Poisson regression. Of 459 patients included, there were 404 HFHs before and 179 after implantation. Compared with pre-implantation, 30 day all-cause readmission [incidence rate ratio (IRR): 0.55 (0.39-0.77), P = 0.0006] and 90 day all cause readmission rates were lower post-implantation [IRR: 0.45 (0.35-0.58), P < 0.0001]. The effect of PAP sensor implantation on 90 day all-cause readmission incidence rates was consistent across multiple subgroups. CONCLUSIONS: Across a large hospital network, ambulatory haemodynamic monitoring was associated with lower HFH rates, as well as 30 and 90 day all-cause readmission rates. This supports the utility of ambulatory PAP monitoring to improve HF management in the era of value-based medicine.
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Valika et al. (2022) conducted a cohort in Heart failure (n=459). Ambulatory pulmonary artery pressure (PAP) monitoring vs. Pre-implantation period was evaluated on 90 day all-cause readmission rates (IRR 0.45, 95% CI 0.35-0.58, p=< 0.0001). Ambulatory pulmonary artery pressure monitoring was associated with lower 90-day all-cause readmission rates compared to pre-implantation (IRR 0.45; 95% CI 0.35-0.58; P<0.0001).
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