Key result
Percutaneous left atrial appendage occlusion and surgical exclusion demonstrate a significant decrease in bleeding while maintaining efficacy in cardioembolism prevention for patients with contraindications to long-term oral anticoagulation.
Why the study?
Knowledge of different left atrial appendage closure techniques is necessary to individualize procedures according to patient anatomy and pre-procedural imaging evaluations.
This review provides an overview of different left atrial appendage closure systems and imaging methods to individualize procedures based on patient anatomy.
May support LAA closure options in anticoagulation-intolerant AF; leaves open need for randomized confirmation.
Several studies in literature have shown that 90% of emboli related to non-valvular atrial fibrillation originate from left atrial appendage. Percutaneous closure or surgical exclusion of left atrial appendage in patients with high bleeding and high cardioembolic risk is currently a well established procedure in literature, clinical practice and guidelines. Knowledge of different techniques of left atrial appendage closure is necessary to individualize the procedure according to the patient anatomy and pre-procedural imaging evaluations. In this review the authors will evaluate different left atrial appendage closure systems and the different pre and intra procedural imaging methods.
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Guarracini et al. (2022) conducted a review in Non-valvular atrial fibrillation. Left atrial appendage occlusion (LAAO) and surgical exclusion vs. Oral anticoagulation was evaluated. Percutaneous left atrial appendage occlusion and surgical exclusion demonstrate a significant decrease in bleeding while maintaining efficacy in cardioembolism prevention for patients with contraindications to long-term oral anticoagulation.
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