Why the study?
Does hyperinsulinaemia increase long-term mortality in non-diabetic patients following acute myocardial infarction?
Population
494 patients with a verified acute myocardial infarction and no history of diabetes
Comparison
Hyperinsulinaemia (high fasting plasma insulin) vs Normal or lower fasting plasma insulin levels
Design
Cohort
Follow-up
6-8 years
Authors
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May identify higher-risk non-diabetic post-MI patients; hypothesis-generating and requires prospective trials before changing practice.
Does hyperinsulinaemia increase long-term mortality in non-diabetic patients following acute myocardial infarction?
High fasting plasma insulin is an independent risk factor for long-term all-cause mortality in non-diabetic patients following acute myocardial infarction.
Camilla Kragelund (2004) studied this question.
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