Effect of age on short and long-term mortality in patients admitted to hospital with congestive heart failure
Why the study?
Does advancing age increase short and long-term mortality in patients hospitalized with congestive heart failure?
Population
Consecutive patients admitted to 34 hospitals with congestive heart failure, mean age 71.7+/-10.2 years, 60%…
Design
Cohort
Follow-up
30 days and 5-8 years
Authors
Discussion
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Overview
Age independently predicts HF mortality; supports risk stratification yet leaves open age-specific interventions.
Key Points
- To examine how age affects mortality risks in patients hospitalized with congestive heart failure (CHF).
- Consecutive patients hospitalized with CHF at 34 hospitals were registered over 2 years.
- Mean age of participants was 71.7 years, with data on survival status collected after 30 days and 5-8 years.
- Prevalence of comorbidities like hypertension and diabetes along with LV systolic dysfunction were assessed.
- Age was an independent predictor of short-term mortality with a risk ratio (RR) of 1.23 (95% CI 1.04-1.47) per 10-year increase.
- Long-term mortality significantly increased with age, RR 1.55 (1.50-1.61).
- In patients with LV systolic dysfunction, RR per 10-year increase was 1.29; for preserved systolic function, RR was 1.57 (1.43-1.72).
Structured PICO
Does advancing age increase short and long-term mortality in patients hospitalized with congestive heart failure?
P
Population
Consecutive patients admitted to 34 hospitals with congestive heart failure (CHF), mean age 71.7+/-10.2 years, 60% male, 63% NYHA class III-IV, 41% with moderate to severe LV systolic dysfunction.
O
Outcome
Short-term (30 days) and long-term (5-8 years) mortalityhard clinical
Advancing age is an independent predictor of both short- and long-term mortality in patients hospitalized with congestive heart failure, with a significant interaction with LV ejection fraction.
Cite This Study
Gustafsson et al. (2004) studied this question.