Why the study?
Does return to a compensated state after short-term inotropic therapy reduce venous endothelial cell activation in patients with decompensated CHF?
Population
15 patients with decompensated chronic heart failure requiring transient inotropic support, and 6…
Comparison
Short-term inotropic therapy to achieve a… vs Healthy controls and within-subject comparison
Design
Cohort
Follow-up
24 hours after discontinuation of short-term inotropic…
Authors
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Reversible endothelial activation in decompensated HF may subside with compensation; hypothesis-generating and should not yet change practice.
Does return to a compensated state after short-term inotropic therapy reduce venous endothelial cell activation in patients with decompensated CHF?
Clinical decompensation in heart failure is associated with reversible venous endothelial activation that subsides upon return to a compensated state following short-term inotropic therapy.
Colombo et al. (2004) studied this question.
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