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What are the safety and efficacy outcomes of epicardial catheter ablation for drug-resistant recurrent ventricular tachycardia?
What are the safety and efficacy outcomes of epicardial catheter ablation for drug-resistant recurrent ventricular tachycardia?
Epicardial catheter ablation for drug-resistant recurrent ventricular tachycardia provides good immediate success rates, particularly in non-ischemic and granulomatous myocarditis, with an acceptable safety profile.
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May support epicardial ablation for refractory VT in selected patients; leaves open need for randomized trials to confirm outcomes.
BACKGROUND AND AIM: Epicardial approach to VT ablation increases the success rate of ablation but is not without complications. We studied the safety and efficacy of epicardial VT ablations performed at our institute. METHODS: All patients who underwent epicardial VT ablation at our institute were studied retrospectively. The outcome of VT ablation was among three groups: ischaemic cardiomyopathy (ICM), non-ischaemic cardiomyopathy (NICM) and granulomatous myocarditis (GM). Safety outcomes assessed included all complications considered to be due to pericardial access or epicardial mapping/ablation. RESULTS: A total of 54 patients (total 119 VTs, mean 2.2 (0.9)) were taken up for ablation procedure through epicardial access. Mean age: 47 (10) years, males: 83%. All patients had drug resistant recurrent VTs. The epicardial procedure was abandoned in three patients due to access issues; percutaneous sub-xiphoid access was employed in 48 and surgical approach in four patients. Complete success was achieved in 59% and partial success in 76%. The outcomes were poor in ICM patients as compared to those with GM and NICM. Overall success rates for all clinical VTs were 89% in GM, 90% in NICM and 67% in ICM. Success rates for epicardial VT ablation were 94%, 85% and 78% respectively for GM, NICM and ICM. Procedure related complications occurred in six patients. CONCLUSION: Epicardial ablation for VT offers good immediate outcomes with acceptable safety profile.
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Pandian et al. (2016) studied this question.
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