Joint and dose‐dependent associations between aerobic and muscle‐strengthening activity with depression: A cross‐sectional study of 1.48 million adults between 2011 and 2017
Key result
Combining moderate-to-vigorous physical and muscle-strengthening activity is linked to ~46% lower depression prevalence.
- PR 0.54-0.63
- n=1,477,981
Why the study?
Epidemiological studies describing the associations between different physical activity modes, such as aerobic versus muscle-strengthening exercise, with depression are limited.
Does combining aerobic and muscle-strengthening activity reduce the prevalence of depression in adults?
Population
1,477,981 adults (≥18 years) across four US health surveillance surveys (2011-2017)
Comparison
Varying combinations of MVPA and MSA vs inactive (0 MVPA min/week and MSA 0 times/week)
Design
Cross-sectional analysis of pooled survey data
Authors
Discussion
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Member takes
Implication
Supports combined activity recommendations; cross-sectional data leaves causality open for prospective trials.
Study Design
Type
Cross-Sectional (n=1,477,981)
Multicenter
Yes
Structured PICO
Does combining aerobic and muscle-strengthening activity reduce the prevalence of depression in adults?
P
Population
1,477,981 adults (≥18 years) from four pooled U.S. health surveillance surveys (2011-2017)
I
Intervention
Various combinations of moderate-to-vigorous-intensity physical activity (MVPA) and muscle-strengthening activity (MSA), up to ≥300 MVPA min/week and MSA ≥4 times/week
C
Comparator
Inactive reference group (0 MVPA min/week and MSA 0 times/week)
O
Outcome
Self-reported clinically diagnosed depressionpatient reported
Main Result
Effect estimate: PR 0.54-0.63
A physical activity routine combining aerobic and muscle-strengthening activity is associated with the lowest prevalence of depression in adults.
Cite This Study
Bennie et al. (2019) conducted a cross-sectional in Depression (n=1,477,981). Moderate-to-vigorous-intensity physical activity (MVPA) and muscle-strengthening activity (MSA) vs. No MVPA and no MSA was evaluated on Self-reported clinically diagnosed depression (PR 0.54-0.63). Combining moderate-to-vigorous physical activity (≥300 min/week) and muscle-strengthening activity (≥2 times/week) was associated with the lowest prevalence of depression (PR 0.54-0.63).