What question did this study set out to answer?

To evaluate differences in clinical and anatomical characteristics between elderly patients undergoing percutaneous coronary intervention versus bypass grafting for non-ST elevation acute coronary syndrome, and to determine predictors of in-hospital mortality.

June 25, 2025Ukrainian journal of cardiovascular surgeryOpen Access

Choice of Myocardial Revascularization Strategy in Elderly Patients with Non-ST Elevation Acute Coronary Syndrome

Q: What are the key findings of this study?

In patients ≥65 years with non-ST elevation acute coronary syndrome, in-hospital mortality did not differ between percutaneous coronary intervention and coronary artery bypass grafting.

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Non-ST elevation acute coronary syndrome (n=124). Intervention: Percutaneous coronary intervention (PCI) vs. Coronary artery bypass grafting (CABG). Primary outcome: In-hospital mortality.

View Full Paper

Ask AI

Bookmark

Key result

PCI shows no in-hospital mortality difference versus CABG in NSTE-ACS patients ≥65 years.

n=124

Why the study?

To identify clinical and demographic differences in elderly patients with non-ST elevation ACS undergoing PCI versus CABG, and to examine factors influencing in-hospital mortality.

Does percutaneous coronary intervention compared to coronary artery bypass grafting affect in-hospital mortality in patients aged ≥65 years with non-ST elevation acute coronary syndrome?

Population

124 patients aged ≥65 years with non-ST elevation acute coronary syndrome

Comparison

PCI vs CABG

Design

Retrospective single-center observational study

Follow-up

In-hospital

Authors

SKSviatoslav A. KalashnikovAmosov National Institute of Cardiovascular Surgery SSSergii V. SaloAmosov National Institute of Cardiovascular Surgery

Discussion

Member takes

Overview

Supports individualized revascularization choices in elderly NSTE-ACS; leaves open need for randomized long-term outcome data.

Key Points

To evaluate differences in clinical and anatomical characteristics between elderly patients undergoing percutaneous coronary intervention versus bypass grafting for non-ST elevation acute coronary syndrome, and to determine predictors of in-hospital mortality.
Retrospective, single-center observational study analyzing 124 patients aged ≥65 years diagnosed with non-ST elevation acute coronary syndrome.
Patients underwent myocardial revascularization via percutaneous coronary intervention (n = 90, 72.6%) or coronary artery bypass grafting (n = 34, 27.4%).
Patients undergoing bypass surgery had significantly higher mean SYNTAX scores (36.2 ± 12.7 vs 24.4 ± 12.5; p < 0.001) and longer hospital stays (median 13 vs 6 days; p < 0.001), whereas percutaneous intervention patients presented more frequently with acute coronary occlusion (p = 0.018).
In-hospital mortality did not differ significantly between revascularization strategies, but was associated with older age (p = 0.04), longer stay (p = 0.009), myocardial infarction (p < 0.001), chronic kidney disease (p < 0.001), prior stroke (p = 0.003), acute occlusion (p = 0.021), and previous bypass surgery (p = 0.013).

Study Design

Type

Observational (n=124)

Multicenter

Structured PICO

Does percutaneous coronary intervention compared to coronary artery bypass grafting affect in-hospital mortality in patients aged ≥65 years with non-ST elevation acute coronary syndrome?

Population

124 patients aged ≥65 years with non-ST elevation acute coronary syndrome (NSTE-ACS), median age 72, 65.3% male, single-center retrospective cohort in Ukraine.

Intervention

Percutaneous coronary intervention (PCI)

Comparator

Coronary artery bypass grafting (CABG)

Outcome

In-hospital mortalityhard clinical

In elderly patients with NSTE-ACS, PCI and CABG showed no significant difference in in-hospital mortality, though CABG patients had more complex coronary anatomy.

Limitations

retrospective single-center design
relatively small sample size, especially in CABG group
lack of long-term follow-up data

Cite This Study

Kalashnikov et al. (2025) conducted an observational in Non-ST elevation acute coronary syndrome (n=124). Percutaneous coronary intervention (PCI) vs. Coronary artery bypass grafting (CABG) was evaluated on In-hospital mortality. In patients ≥65 years with non-ST elevation acute coronary syndrome, in-hospital mortality did not differ between percutaneous coronary intervention and coronary artery bypass grafting.

synapsesocial.com/papers/6a08cfa402034f20cae4a682 https://doi.org/10.63181/ujcvs.2025.33(2).27-33

Topics

Percutaneous coronary intervention Chronic total occlusion PCI

View Full Paper

Ask AI

Bookmark

June 25, 2025Ukrainian journal of cardiovascular surgeryOpen Access

Choice of Myocardial Revascularization Strategy in Elderly Patients with Non-ST Elevation Acute Coronary Syndrome

View Full Paper

Ask AI

Bookmark

Key result

PCI shows no in-hospital mortality difference versus CABG in NSTE-ACS patients ≥65 years.

n=124

Why the study?

To identify clinical and demographic differences in elderly patients with non-ST elevation ACS undergoing PCI versus CABG, and to examine factors influencing in-hospital mortality.

Does percutaneous coronary intervention compared to coronary artery bypass grafting affect in-hospital mortality in patients aged ≥65 years with non-ST elevation acute coronary syndrome?

Population

124 patients aged ≥65 years with non-ST elevation acute coronary syndrome

Comparison

PCI vs CABG

Design

Retrospective single-center observational study

Follow-up

In-hospital

Authors

SKSviatoslav A. KalashnikovAmosov National Institute of Cardiovascular Surgery SSSergii V. SaloAmosov National Institute of Cardiovascular Surgery

Discussion

Member takes

Overview

Supports individualized revascularization choices in elderly NSTE-ACS; leaves open need for randomized long-term outcome data.

Key Points

To evaluate differences in clinical and anatomical characteristics between elderly patients undergoing percutaneous coronary intervention versus bypass grafting for non-ST elevation acute coronary syndrome, and to determine predictors of in-hospital mortality.
Retrospective, single-center observational study analyzing 124 patients aged ≥65 years diagnosed with non-ST elevation acute coronary syndrome.
Patients underwent myocardial revascularization via percutaneous coronary intervention (n = 90, 72.6%) or coronary artery bypass grafting (n = 34, 27.4%).
Patients undergoing bypass surgery had significantly higher mean SYNTAX scores (36.2 ± 12.7 vs 24.4 ± 12.5; p < 0.001) and longer hospital stays (median 13 vs 6 days; p < 0.001), whereas percutaneous intervention patients presented more frequently with acute coronary occlusion (p = 0.018).
In-hospital mortality did not differ significantly between revascularization strategies, but was associated with older age (p = 0.04), longer stay (p = 0.009), myocardial infarction (p < 0.001), chronic kidney disease (p < 0.001), prior stroke (p = 0.003), acute occlusion (p = 0.021), and previous bypass surgery (p = 0.013).

Study Design

Type

Observational (n=124)

Multicenter

Structured PICO

Does percutaneous coronary intervention compared to coronary artery bypass grafting affect in-hospital mortality in patients aged ≥65 years with non-ST elevation acute coronary syndrome?

Population

124 patients aged ≥65 years with non-ST elevation acute coronary syndrome (NSTE-ACS), median age 72, 65.3% male, single-center retrospective cohort in Ukraine.

Intervention

Percutaneous coronary intervention (PCI)

Comparator

Coronary artery bypass grafting (CABG)

Outcome

In-hospital mortalityhard clinical

In elderly patients with NSTE-ACS, PCI and CABG showed no significant difference in in-hospital mortality, though CABG patients had more complex coronary anatomy.

Limitations

retrospective single-center design
relatively small sample size, especially in CABG group
lack of long-term follow-up data

Cite This Study

synapsesocial.com/papers/6a08cfa402034f20cae4a682 https://doi.org/10.63181/ujcvs.2025.33(2).27-33

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Topics

Percutaneous coronary intervention Chronic total occlusion PCI

View Full Paper

Ask AI

Bookmark