Key result
Biventricular pacing improved heart failure symptoms by at least one NYHA class in 40% of patients with end-stage hypertrophic cardiomyopathy, and increased ejection fraction (p=0.009).
Why the study?
Does biventricular pacing improve symptoms and cardiac remodelling in patients with end-stage hypertrophic cardiomyopathy?
Population
20 patients with non-obstructive end-stage hypertrophic cardiomyopathy, left bundle branch block, and…
Design
Cohort
Follow-up
mean 13±6 months
Authors
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May support biventricular pacing in select end-stage HCM; hypothesis-generating and requires randomized confirmation.
Cohort (n=20)
Does biventricular pacing improve symptoms and cardiac remodelling in patients with end-stage hypertrophic cardiomyopathy?
Biventricular pacing may improve heart failure symptoms and induce reverse cardiac remodelling in a subset of patients with end-stage hypertrophic cardiomyopathy and left bundle branch block.
Rogers et al. (2008) conducted a cohort in End-stage hypertrophic cardiomyopathy (n=20). Biventricular pacing was evaluated on Improvement of at least one NYHA class. Biventricular pacing improved heart failure symptoms by at least one NYHA class in 40% of patients with end-stage hypertrophic cardiomyopathy, and increased ejection fraction (p=0.009).
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