What does this research mean for the field?

Bladder distention and contraction, particularly against a closed bladder neck, induce significant ischemia and hypoxia of the bladder wall. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study investigates how bladder filling, contraction, and outlet obstruction affect blood flow and oxygen levels in the bladder wall.

April 1, 1996The Journal of Urology

Canine Bladder Blood Flow and Oxygenation: Changes Induced by Filling, Contraction and Outlet Obstruction

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Authors

KAKazem M. AzadzoiBoston University MPMichel A. PontariTemple University JVJohn VlachiotisBoston Medical Center

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Implication

Randomized trial examines bladder blood flow changes during filling and obstruction in anesthetized dogs, suggesting critical insights for clinical conditions.

Key Points

This study investigates how bladder filling, contraction, and outlet obstruction affect blood flow and oxygen levels in the bladder wall.
Measured intravesical pressure, bladder flow, oxygen tension, iliac artery blood flow, and systemic blood pressure in anesthetized dogs (N=18).
Assessed effects of bladder filling, contraction, and nerve stimulation on bladder perfusion and oxygenation.
In an empty bladder, blood flow and oxygen tension were higher at the dome compared to the wall, especially during obstruction.
Filling the bladder significantly decreased wall blood flow and oxygen tension regardless of obstruction status.
Strong contractions from pelvic nerve stimulation led to reduced perfusion and oxygenation in both open and closed bladder neck models.

Cite This Study

Azadzoi et al. (1996) studied this question.

synapsesocial.com/papers/6a08d5fb451dd5ba805b64ef https://doi.org/10.1016/s0022-5347(01)66307-9

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Implication

Randomized trial examines bladder blood flow changes during filling and obstruction in anesthetized dogs, suggesting critical insights for clinical conditions.

Canine Bladder Blood Flow and Oxygenation: Changes Induced by Filling, Contraction and Outlet Obstruction

Discussion

Member takes

Implication

Key Points

Cite This Study

Canine Bladder Blood Flow and Oxygenation: Changes Induced by Filling, Contraction and Outlet Obstruction

Discussion

Member takes

Implication

Key Points

Cite This Study

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