Key result
Bladder distension decreases coronary blood flow in dogs via vagal and sympathetic pathways.
Why the study?
Does distension of the urinary bladder affect mean coronary blood flow in anesthetized dogs?
Population
11 dogs anaesthetized with sodium pentobarbitone
Design
Preclinical
Authors
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Alerts to possible reflex coronary effects from bladder distension in anesthetized models; leaves open relevance to awake humans or other species.
Does distension of the urinary bladder affect mean coronary blood flow in anesthetized dogs?
Distension of the urinary bladder reflexly decreases mean coronary blood flow via efferent cardiac vagal and sympathetic pathways in an anesthetized dog model.
Cevese et al. (1991) studied this question. Distension of the urinary bladder vs. Baseline/no distension was evaluated on Mean coronary blood flow. Distension of the urinary bladder reflexly decreased mean coronary blood flow in anesthetized dogs, a response involving efferent cardiac vagal and sympathetic pathways.
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