Why the study?
Does gallbladder distension reduce left circumflex blood flow in anesthetized pigs?
Population
21 pigs anesthetized with sodium pentobarbitone (n=16) or alpha-chloralose (n=5)
Comparison
Gallbladder distension with volumes of Ringer's… vs Baseline (prior to distension)
Design
Preclinical
Authors
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May indicate a gallbladder-coronary reflex in ischemia; hypothesis-generating and requires human confirmation.
Does gallbladder distension reduce left circumflex blood flow in anesthetized pigs?
Gallbladder distension induces reflex coronary vasoconstriction mediated by vagal afferents and sympathetic efferents in a porcine model.
Vacca et al. (1996) studied this question.
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