Why the study?
Does passive gastric distension elicit cardiovascular reflexes that increase myocardial oxygen demand in anesthetized cats?
Population
alpha-chloralose anesthetized cats
Comparison
Passive gastric distension with 37 degrees C… vs Baseline (before distension)
Design
Preclinical
Authors
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Suggests gastric distension may raise myocardial O2 demand via splanchnic reflexes in cats; leaves open relevance to postprandial angina in humans.
Does passive gastric distension elicit cardiovascular reflexes that increase myocardial oxygen demand in anesthetized cats?
Passive gastric distension elicits cardiovascular reflexes mediated by the splanchnic nerve that increase myocardial oxygen demand, providing a potential mechanism for postprandial angina in humans.
Longhurst et al. (1981) studied this question.
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