Key result
Hypertension in HCM links to reduced LV GLS compared to normotensives.
Why the study?
Most studies focus on the differential diagnosis between HCM and SAH, but little is known about the magnitude of their association.
Does the presence of systemic arterial hypertension worsen left ventricular global longitudinal strain in patients with hypertrophic cardiomyopathy?
Population
45 patients with HCM and preserved ejection fraction confirmed by magnetic resonance imaging
Comparison
HCM patients with associated SAH vs without associated SAH
Design
Retrospective cross-sectional study
Authors
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May indicate greater myocardial impairment in hypertensive HCM; hypothesis-generating, requiring prospective validation before practice implications.
Cross-Sectional (n=45)
Does the presence of systemic arterial hypertension worsen left ventricular global longitudinal strain in patients with hypertrophic cardiomyopathy?
Absolute Event Rate: -10.29% vs -12.35%
p-value: p=0.0303
The association of systemic arterial hypertension with hypertrophic cardiomyopathy is linked to worse left ventricular global longitudinal strain, indicating greater myocardial impairment.
Gil et al. (2019) conducted a cross-sectional in Hypertrophic cardiomyopathy with and without systemic arterial hypertension (n=45). Systemic arterial hypertension vs. Without systemic arterial hypertension (normotensive) was evaluated on Left ventricular global longitudinal strain (GLS) (p=0.0303). Systemic arterial hypertension in hypertrophic cardiomyopathy patients was associated with lower left ventricular global longitudinal strain compared to normotensives (-10.29% vs -12.35%, p=0.0303).
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