Why the study?
Dilatation and curettage is commonly performed under procedural sedation, prompting a comparison between dexmedetomidine-ketamine and ketamine-propofol for sedation and analgesia.
Does dexmedetomidine-ketamine improve time to onset of sedation and recovery compared to ketamine-propofol in female patients undergoing elective dilatation and curettage?
Population
80 female patients, ASAI and II, 20 and 60 years, scheduled for elective D and C
Comparison
Dexmedetomidine-ketamine vs ketamine-propofol
Design
Prospective randomized double-blind study
Authors
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Dexmedetomidine-ketamine provides a viable alternative for procedural sedation; extends RCT data on combination regimens in ambulatory gynecology.
Does dexmedetomidine-ketamine improve time to onset of sedation and recovery compared to ketamine-propofol in female patients undergoing elective dilatation and curettage?
Dexmedetomidine-ketamine is a safe and effective alternative to ketamine-propofol for procedural sedation during dilatation and curettage, offering comparable onset and recovery times with potentially better postoperative analgesia.
Kaasat et al. (2025) studied this question.
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