Key result
Exercise training moderates resting sympathetic excess in HFrEF despite scant data during exertion.
Why the study?
Recording sympathetic nerve firing during exercise is challenging, leaving data acquired during exercise scant and varying by exercise modality in HFrEF.
Does exercise training moderate sympathetic neural responses in experimental and human HFrEF?
Population
Experimental models and humans with HFrEF
Design
Review
Authors
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Supports exercise training to moderate resting sympathetic excess in HFrEF; leaves open effects on nerve firing during exercise.
Does exercise training moderate sympathetic neural responses in experimental and human HFrEF?
This review highlights the role of exercise training in moderating sympathetic excess in HFrEF and underscores the need for further research on neural afferent mechanisms during exercise.
Notarius et al. (2021) conducted a review in Heart failure with reduced ejection fraction (HFrEF). Exercise training was evaluated. Exercise training moderates sympathetic excess at rest in heart failure with reduced ejection fraction, though data on sympathetic nerve firing during exercise remain scant.
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