Why the study?
Are baseline risk factors or changes in risk factors associated with the progression of common carotid intima-media thickness in adults aged 45-64?
Population
Population-based cohort, age 45-64 years, n = 15,792, sampled in four areas of the United States.
Design
Cohort
Follow-up
1987-1998
Authors
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Supports risk factor monitoring in middle age; leaves open whether modification alters IMT progression.
Are baseline risk factors or changes in risk factors associated with the progression of common carotid intima-media thickness in adults aged 45-64?
Established risk factors for coronary heart disease are significantly associated with the rate of progression of subclinical atherosclerosis as measured by carotid intima-media thickness.
Lloyd E. Chambless (2002) studied this question.
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