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February 1, 1996Arteriosclerosis Thrombosis and Vascular Biology

Relation of Intima-Media Thickness to Atherosclerotic Plaques in Carotid Arteries

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Why the study?

Is increased common carotid artery intima-media thickness associated with the presence of atherosclerotic plaques and specific cardiovascular risk factors in older adults?

Population

1,272 adults (516 men and 756 women) aged 59 to 71 years recruited for the European Vascular Aging Study

Design

Cross-sectional

Authors

CBClaire Bonithon‐KoppInsermPTPierre‐Jean TouboulUniversité Claude Bernard Lyon 1CBClaudine BerrUniversitat Autònoma de Barcelona

Discussion

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Implication

IMT increase signals plaque presence in older adults; extends cross-sectional links but leaves open prospective risk prediction value.

Structured PICO

Is increased common carotid artery intima-media thickness associated with the presence of atherosclerotic plaques and specific cardiovascular risk factors in older adults?

P
Population
1,272 adults (516 men and 756 women) aged 59 to 71 years recruited for the European Vascular Aging Study
I
Intervention
B-mode ultrasonography to measure intima-media thickness of the common carotid artery and sites of plaque in the internal carotid artery and bifurcations
O
Outcome
Relation between common carotid artery intima-media thickness and the presence and severity of atherosclerotic plaquesurrogate

Increases in common carotid artery intima-media thickness are independently associated with the presence of local atherosclerotic plaques and traditional cardiovascular risk factors.

Cite This Study

Bonithon‐Kopp et al. (1996) studied this question.

synapsesocial.com/papers/6a0fe9fb5725bbd5cc603ca7https://doi.org/10.1161/01.atv.16.2.310
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Carotid artery intimal-medial thickness distribution in general populations as evaluated by B-mode ultrasound. ARIC Investigators.1993 · 726 citations
  2. 2Determinants of carotid intima‐media thickness: a population‐based ultrasonography study in Eastern Finnish men1991 · 568 citations
  3. 3Distribution and correlates of sonographically detected carotid artery disease in the Cardiovascular Health Study. The CHS Collaborative Research Group.1992 · 844 citations
  4. 4Evidence for in vivo carotid and femoral wall thickening in human hypertension. Groupe de Prévention Cardio-vasculaire en Médecine du Travail.1993 · 167 citations
  5. 5Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients. Study by ultrasound high-resolution B-mode imaging.1994 · 48 citations