Key result
Percutaneous WATCHMAN seals an incompletely ligated LAA with a trivial ~1.5 mm peri-device leak.
Why the study?
Although percutaneous measures have been analyzed for peri-device leak, the use of percutaneous occluder devices in surgically occluded left atrial appendages is far less studied.
Does percutaneous LAA occluder device deployment improve peri-device leak in a patient with prior surgical ligation with incomplete exclusion?
Case Report (n=1)
Does percutaneous LAA occluder device deployment improve peri-device leak in a patient with prior surgical ligation with incomplete exclusion?
Percutaneous LAA occluder device deployment is a feasible option for patients with AF and incomplete surgical LAA exclusion to allow de-escalation of anticoagulation.
May support feasibility of WATCHMAN deployment after incomplete surgical LAA ligation; hypothesis-generating for anticoagulation de-escalation trials.
Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and the most common cause of cardioembolic stroke. The left atrial appendage (LAA) is the main source of thrombus formation in patients with AF. Therapies include use of percutaneous LAA closure devices, or surgical LAA occlusion (LAAO). Despite these options, complete closure of the LAA is not always achieved, and residual communication between the LAA and atrium may result in increased thrombus formation. Although studies have analysed the use of percutaneous measures such as coils, plugs, or second occluder device deployment in LAA with peri-device leak (PDL), use of percutaneous occlude devices in surgically occluded LAA is far less studied. Case summary: We present a case of a 79-year-old female patient who underwent LAAO device deployment within a surgically occluded LAA with PDL. She underwent 27 mm LAAO device (WATCHMANTM) deployment and all the P.A.S.S. (Position, Anchor, Size, and Seal) criteria were satisfied. Only 1.4 mm PDL was present. She was continued on apixaban and aspirin post-operatively. Post-operative transoesophageal echocardiogram at 6 weeks demonstrated trivial PDL measuring 1.49 mm. Patient was continued on aspirin and clopidogrel, with discontinuation of apixaban. Discussion: Percutaneous LAAO device deployment in previously surgically ligated LAA with incomplete exclusion is a potential therapeutic option for patients with AF and a high bleeding risk seeking a minimally invasive strategy, in an attempt to de-escalate anticoagulation therapy.
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Fadel et al. (2024) conducted a case report in Atrial fibrillation with prior surgical LAA ligation and incomplete exclusion (n=1). Percutaneous left atrial appendage occluder device (WATCHMAN) was evaluated on Peri-device leak size. Percutaneous deployment of a 27 mm WATCHMAN device in a surgically ligated left atrial appendage with incomplete exclusion resulted in a trivial 1.49 mm peri-device leak at 6 weeks.
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