Key result
MLP immunoreactivity was decreased by approximately 50% (P<0.05) in the left ventricular myocardium of patients with chronic heart failure compared with non-failing donor hearts.
Authors
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MLP decrease in failing myocardium is hypothesis-generating; leaves open its mechanistic role and therapeutic potential in chronic HF.
Observational
Effect estimate: Decreased ~50%
p-value: p=<0.05
Zolk et al. (2000) conducted an observational in Chronic heart failure (dilated or ischemic cardiomyopathy). Chronic heart failure vs. Non-failing donor hearts was evaluated on MLP immunoreactivity in the left ventricular myocardium (Decreased ~50%, p=<0.05). MLP immunoreactivity was decreased by approximately 50% (P<0.05) in the left ventricular myocardium of patients with chronic heart failure compared with non-failing donor hearts.
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