Key result
Endothelins are potent vasoconstrictors with raised plasma concentrations in various clinical conditions, suggesting a significant role in several pathophysiological processes.
Design
Review
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Endothelin involvement in disease is reinforced; leaves open targeted therapies without prospective trials.
Endothelins are potent vasoconstrictors with diverse biological activities and elevated levels in various pathophysiological conditions, suggesting a significant role in cardiovascular and systemic diseases.
Leppäluoto et al. (1992) conducted a review in Endothelin-related pathophysiology. Endothelins was evaluated. Endothelins are potent vasoconstrictors with raised plasma concentrations in various clinical conditions, suggesting a significant role in several pathophysiological processes.
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