Key result
Larger immediate contacting and redundant coaptation regions after undersized ring annuloplasty are linked to 6-month recurrence.
Why the study?
Long-term outcomes of mitral valve repair for ischemic mitral regurgitation remain unpredictable, partly because echocardiography cannot reliably quantify the coaptation zone.
Does mitral valve coaptation area immediately postrepair predict regurgitation recurrence at 6 months in patients undergoing undersized ring annuloplasty for ischemic mitral regurgitation?
Population
Patients with ischemic mitral regurgitation from an extant database
Comparison
Pre-repair vs post-repair with undersized ring annuloplasty, stratified by recurrence
Design
Simulation-based shape-matching imaging study on an extant database
Follow-up
6 months postrepair
Authors
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Larger immediate coaptation area may not ensure durability after undersized annuloplasty for ischemic MR; leaves open optimal coaptation targets for future trials.
Observational
Does mitral valve coaptation area immediately postrepair predict regurgitation recurrence at 6 months in patients undergoing undersized ring annuloplasty for ischemic mitral regurgitation?
p-value: p=< .05
Larger leaflet coaptation area immediately after undersized ring annuloplasty for ischemic mitral regurgitation is associated with recurrence at 6 months, suggesting it may not be a reliable target for repair durability.
Simonian et al. (2022) conducted an observational in Ischemic mitral regurgitation. Undersized ring annuloplasty vs. No recurrence at 6 months was evaluated on Mitral valve coaptation geometry (contacting and redundant regions) (p=< .05). Undersized ring annuloplasty resulted in larger contacting and redundant coaptation regions immediately postrepair in patients with recurrence at 6 months compared to those with no recurrence (P<.05).
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