Key result
Human gene expression studies in adipose tissue reveal that obesity is a chronic inflammatory illness, with specific biomarkers regulated during weight loss programs based on calorie restriction.
Population
Obese subjects
Design
Review
Authors
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Adipose gene expression profiles reinforce obesity as inflammatory; extends prior macrophage observations but leaves open clinical translation.
This review highlights the role of adipose tissue inflammation in obesity and discusses how weight loss interventions modulate inflammatory gene expression.
Clément et al. (2007) conducted a review in Obesity. Human gene expression studies in adipose tissue reveal that obesity is a chronic inflammatory illness, with specific biomarkers regulated during weight loss programs based on calorie restriction.
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