Key result
Lower BP targets cut major CV events by ~19% versus standard targets in hypertensive adults.
Why the study?
To systematically evaluate evidence on self-measured BP versus office BP, optimal BP-lowering targets, and comparative benefits and harms of first-line antihypertensive drug classes.
Does self-measured blood pressure without other augmentation improve systolic blood pressure control in adults with hypertension compared to office-measured blood pressure?
Meta-Analysis
Does self-measured blood pressure without other augmentation improve systolic blood pressure control in adults with hypertension compared to office-measured blood pressure?
Effect estimate: RR 0.81 (95% CI 0.70-0.94)
Self-measured blood pressure without additional support provides a modest, short-term improvement in systolic BP at 6 months compared to routine office care, but this benefit is not sustained at 12 months.
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Self-measured BP yields modest systolic reductions at 6 months but not 12; reinforces targeting <130 mm Hg to lower MI and stroke risk.
Reboussin et al. (2017) conducted a meta-analysis in Hypertension. Lower blood pressure target vs. Standard or higher blood pressure target was evaluated on Major cardiovascular events (RR 0.81, 95% CI 0.70-0.94). A lower blood pressure target significantly reduced the risk of major cardiovascular events by 19% compared to a standard or higher blood pressure target in adults with hypertension.
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