Key result
Nucleotide sequence analysis of the human c-myc locus reveals a highly conserved gene product that shares homologous coding regions with chicken c-myc and the MC29 viral oncogene.
Population
Human cellular c-myc, chicken c-myc, and v-myc of myelocytomatosis virus MC29
Design
Preclinical
Authors
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No immediate clinical implications; extends myc homology data but leaves open functional roles in human disease.
The study identifies highly conserved coding regions and distinct structural domains across human, chicken, and viral myc genes, highlighting evolutionary conservation of the gene product.
Watson et al. (1983) studied this question. Nucleotide sequence analysis of the human c-myc locus reveals a highly conserved gene product that shares homologous coding regions with chicken c-myc and the MC29 viral oncogene.
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