Structure and transcription of the cellular homolog (c-myb) of the avian myeloblastosis virus transforming gene (v-myb)
Population
Molecular clones containing the chicken cellular homolog of the avian myeloblastosis virus oncogene
Design
Preclinical
Authors
Discussion
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Member takes
Overview
May distinguish c-myb from v-myb products; leaves open functional consequences in oncogenesis.
Structured PICO
P
Population
Molecular clones containing the chicken cellular homolog (c-myb) of the avian myeloblastosis virus oncogene (v-myb)
I
Intervention
Molecular cloning, restriction endonuclease mapping, hybridization, and transcript analysis
O
Outcome
Structure and transcription of the c-myb gene
The identification of exon sequences in c-myb outside the regions of homology with v-myb suggests that the v-myb and c-myb gene products may differ significantly.
Cite This Study
Gonda et al. (1983) studied this question.