Key result
Contact force-sensing focal PFA successfully treats incessant LAA apex AT without recurrence.
Why the study?
Focal atrial tachycardias originating from the left atrial appendage apex are rare and challenging to treat due to a high risk of cardiac perforation with conventional radiofrequency ablation.
Does contact force-sensing focal pulsed-field ablation safely and effectively treat incessant atrial tachycardia originating from the left atrial appendage apex?
Case Report (n=1)
Does contact force-sensing focal pulsed-field ablation safely and effectively treat incessant atrial tachycardia originating from the left atrial appendage apex?
Focal pulsed-field ablation using a contact force-sensing catheter may be a safe and effective alternative for treating challenging atrial tachycardias originating from the left atrial appendage apex without the high risk of perforation seen with radiofrequency ablation.
May offer safer ablation for LAA-apex AT; leaves open generalizability beyond single-case reports.
BACKGROUND: Focal atrial tachycardias (ATs) originating from the left atrial appendage (LAA) apex are rare and challenging to treat given the high risk of cardiac perforation with conventional radiofrequency ablation. CASE SUMMARY: A 15-year-old girl with an incessant AT arising from the LAA apex was successfully and safely treated using a novel contact force-sensing focal pulsed-field ablation (PFA) catheter with 10 applications. The patient remained asymptomatic, without tachycardia recurrence throughout a 4-month follow-up. DISCUSSION: This first report demonstrates the safety and efficiency of PFA for AT arising from the LAA apex. TAKE-HOME MESSAGES: For focal ATs originating from the LAA apex, a contact force-sensing focal PFA catheter is a viable alternative therapy. This approach enables targeted ablation of the arrhythmogenic focus while mitigating perforation risk, thus offering clinical utility for this challenging subset of focal ATs.
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Yang et al. (2026) conducted a case report in Incessant atrial tachycardia originating from the left atrial appendage apex (n=1). Contact force-sensing focal pulsed-field ablation (PFA) catheter was evaluated on Tachycardia recurrence and safety. A contact force-sensing focal pulsed-field ablation catheter successfully treated an incessant atrial tachycardia from the left atrial appendage apex with 0 recurrences over a 4-month follow-up.
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