Key result
Animal model tests speckle tracking echocardiography for detecting PEEP-induced RV deterioration.
Why the study?
Does speckle tracking echocardiography (STE) determine deterioration in right ventricle function induced by positive end-expiratory pressure (PEEP) compared to fractional area change (FAC) in an animal model?
Does speckle tracking echocardiography (STE) determine deterioration in right ventricle function induced by positive end-expiratory pressure (PEEP) compared to fractional area change (FAC) in an animal model?
Answers are grounded in this paper and cite their sources.
Speckle tracking may detect PEEP-induced RV changes in animals; leaves open clinical utility versus FAC pending human validation.
Background Right ventricle (RV) dysfunction and hypotension can be induced by high levels of positive end-expiratory pressure (PEEP). We sought to determine in an animal model if a novel ultrasound analysis technique: speckle tracking echocardiography (STE), could determine deterioration in RV function induced by PEEP and to compare this to a conventional method of RV analysis: fractional area change (FAC). STE is a sensitive, angle-independent method for describing cardiac deformation (‘strain’) and is particularly useful in analyzing RV function as has been shown in pulmonary hypertension cohorts.
No takes yet. Share an insight, caveat, or question.
Orde et al. (2014) studied Right ventricle dysfunction. Speckle tracking echocardiography (STE) vs. Fractional area change (FAC) was evaluated on Deterioration in right ventricle function. An animal model study was designed to evaluate whether speckle tracking echocardiography could determine deterioration in right ventricular function induced by positive end-expiratory pressure.
Synapse has enriched 10 related papers. Consider them for comparative context: