Key result
Overdistension of the right ventricle with abnormally high pressures markedly diminished vasomotor tonus in both coronary trees, although left heart performance did not vary appreciably.
Why the study?
How does right ventricular overdistension affect coronary blood flow and vasomotor tonus?
Population
Experimental model (specific model not explicitly stated in abstract)
Comparison
Alteration of left or right ventricular… vs Normal ventricular performance
Design
Preclinical
Authors
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RV overdistension may impair bilateral coronary vasomotor tone without LV effects; leaves open relevance to human right heart failure.
How does right ventricular overdistension affect coronary blood flow and vasomotor tonus?
Right ventricular overdistension leads to a marked decrease in vasomotor tonus in both coronary trees, independent of left heart performance.
Cecil E. Cross (1962) studied this question. Alteration of ventricular performance was evaluated on Coronary blood flow and vasomotor tonus. Overdistension of the right ventricle with abnormally high pressures markedly diminished vasomotor tonus in both coronary trees, although left heart performance did not vary appreciably.
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