July 1, 1985Circulation ResearchOpen Access

Role of afterload in determining regional right ventricular performance during coronary underperfusion in dogs.

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Why the study?

Does right ventricular systolic pressure affect regional wall motion during coronary underperfusion in dogs?

Structured PICO

Does right ventricular systolic pressure affect regional wall motion during coronary underperfusion in dogs?

Population

13 open-chest dogs

Intervention

Alteration of coronary perfusion pressure (right coronary artery perfused through a shunt from a carotid artery) in the presence or absence of right ventricular hypertension (pulmonary artery banding)

Comparator

Different levels of coronary perfusion pressure; presence vs absence of right ventricular hypertension

Outcome

Regional systolic shortening of the right ventricular free wall measured by sonomicrometrysurrogate

Right ventricular systolic pressure is an important determinant of regional wall motion during coronary underperfusion in a canine model.

Discussion

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Implication

RV systolic pressure may set ischemia thresholds in canine RV; hypothesis-generating for clinical RV protection strategies.

Cite This Study

Urabe et al. (1985) studied this question.

synapsesocial.com/papers/6a73534664cdd4095c2c2533 https://doi.org/10.1161/01.res.57.1.96

View Full Paper

Ask AI

Bookmark

Role of afterload in determining regional right ventricular performance during coronary underperfusion in dogs.

Structured PICO

Discussion

Implication

Cite This Study

Role of afterload in determining regional right ventricular performance during coronary underperfusion in dogs.

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider