What does this research mean for the field?

Elevated right ventricular pressure progressively throttles systolic right coronary blood flow, leading to retrograde systolic flow and restricted perfusion to the inner layers of the right myocardium in severe cases of right ventricular hypertension. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1976Circulation Research

Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures.

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Population

Well trained normal dogs and dogs with pulmonic stenosis

Comparison

Measurement of phasic right coronary blood flow… vs Normotensive dogs vs. dogs with pulmonic stenosis

Design

Preclinical

Authors

HLH. S. LowensohnLöwenstein Medical (Germany)EKEDWARD M. KHOURIWalter Reed Army Institute of Research DGDonald E. GreggWalter Reed Army Institute of Research

Discussion

Member takes

Implication

Should not change clinical practice in pulmonic stenosis; leaves open pressure-related flow dynamics in human right ventricular hypertension.

Structured PICO

Population

Well trained normal dogs and dogs with pulmonic stenosis

Intervention

Measurement of phasic right coronary blood flow, cardiac output, central aortic blood pressure, and right ventricular pressure using electromagnetic flow transducers and pressure tubes

Comparator

Normotensive dogs vs. dogs with pulmonic stenosis (elevated right ventricular pressures)

Outcome

Phasic right coronary blood flow patterns (including systolic to diastolic flow ratios)surrogate

Cite This Study

Lowensohn et al. (1976) studied this question.

synapsesocial.com/papers/6a1757bf3510de12de8d7cd3 https://doi.org/10.1161/01.res.39.6.760

Topics

Hypertension management

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Implication

Should not change clinical practice in pulmonic stenosis; leaves open pressure-related flow dynamics in human right ventricular hypertension.

Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider