Population
Preclinical heart model (species not specified in abstract)
Comparison
Manipulation of hemodynamic factors, cardiac… vs Control measurements in uninjured hearts and…
Design
Preclinical
Authors
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Questions metabolic autoregulation of coronary flow; hypothesis-generating in animals and leaves open human translation.
Coronary blood flow is primarily determined by mechanical pressure differentials (coronary driving pressure) rather than metabolic demands (cardiac oxygen consumption) under the studied conditions.
Cross et al. (1961) studied this question.
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