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March 1, 1993The Journal of Infectious Diseases

A Mutation in Human Immunodeficiency Virus Reverse Transcriptase and Decline in CD4 Lymphocyte Numbers in Long-Term Zidovudine Recipients

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Authors

MKMichael J. KozalRSRobert W. ShaferMWMark A. Winters

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Kozal et al. (1993) studied this question.

synapsesocial.com/papers/6a09bbb216dfdfe7ed345505https://doi.org/10.1093/infdis/167.3.526
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Also Consider

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  3. 3Detection of human immunodeficiency virus type 1 clinical isolates with reduced sensitivity to zidovudine and dideoxyinosine by RNA.RNA hybridization.1991 · 71 citations
  4. 4Ordered Appearance of Zidovudine Resistance Mutations during Treatment of 18 Human Immunodeficiency Virus-Positive Subjects1992 · 362 citations
  5. 5HIV with Reduced Sensitivity to Zidovudine (AZT) Isolated During Prolonged Therapy1989 · 1,565 citations