Why the study?
US ASCVD management relies on studies in primarily non-Hispanic White subjects, which may cause inaccurate ASCVD risk estimation and inappropriate treatment targeting in Asian populations.
Population
Chinese, Japanese, and Korean people living in the United States and in their native countries
Design
State-of-the-art review
Key result
Current ASCVD risk calculators may inaccurately estimate risk in East Asian populations, highlighting the need to disaggregate data and develop validated, region-specific risk prediction models.
Authors
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Urges caution applying U.S. calculators to East Asians; leaves open validation of region-specific models.
This review highlights that current U.S. ASCVD risk calculators overestimate risk in East Asian populations and emphasizes the need for disaggregated data to develop and validate specific risk models for East Asian immigrants.
Nguyen et al. (2025) conducted a review in Atherosclerotic Cardiovascular Disease. ASCVD Risk Prediction Models was evaluated. Current ASCVD risk calculators may inaccurately estimate risk in East Asian populations, highlighting the need to disaggregate data and develop validated, region-specific risk prediction models.