Key result
Discontinuation of antihypertensive medication led to a period of normotension in 8% of subjects, with 11 maintaining blood pressure control without medication for at least 4 years.
Why the study?
Does discontinuation of antihypertensive medication maintain adequate blood pressure control in hypertensive subjects?
Population
1138 hypertensive subjects from the Framingham Heart Study taking antihypertensive medication at two…
Comparison
Discontinuation of antihypertensive medication vs Continued antihypertensive medication
Design
Cohort
Follow-up
up to 12 years
Authors
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May indicate remission after stopping antihypertensives in a minority; hypothesis-generating and should not yet alter practice.
Cohort (n=1,138)
Does discontinuation of antihypertensive medication maintain adequate blood pressure control in hypertensive subjects?
A small subset of hypertensive patients may experience a period of remission and maintain normal blood pressure without medication for several years.
Andrew L. Dannenberg (1987) conducted a cohort in Hypertension (n=1,138). Discontinuation of antihypertensive medication vs. Continued medication was evaluated on Normotension while not receiving medication. Discontinuation of antihypertensive medication led to a period of normotension in 8% of subjects, with 11 maintaining blood pressure control without medication for at least 4 years.
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