Key result
Failure to adjust hypertension medication when required linked to ~31% lower odds of hypertension control.
Why the study?
The study was conducted to assess compliance with national hypertension treatment guidelines and determine hypertension control rates across hospital facilities of different sizes in Thailand.
Does adherence to hypertension treatment guidelines improve hypertension control rates in hospitals of different sizes in Thailand?
Observational (n=1,406)
Yes
Does adherence to hypertension treatment guidelines improve hypertension control rates in hospitals of different sizes in Thailand?
Failure to comply with hypertension treatment guidelines, specifically regarding medication adjustment, significantly reduces the odds of achieving blood pressure control.
Answers are grounded in this paper and cite their sources.
Supports medication adjustment protocols in hypertension care; leaves open causal effects of guideline adherence on control across Thai hospitals.
A clinical audit of hospitals in Thailand was conducted to assess compliance with the national hypertension treatment guidelines and determine hypertension control rates across facilities of different sizes. Stratified random sampling was used to select sixteen hospitals of different sizes from four provinces. These included community (<90 beds), large (90-120 beds), and provincial (>120 beds) hospitals. Among new cases, the audit determined whether (i) the recommended baseline laboratory assessment was completed, (ii) the initial choice of medication was appropriate based on the patient's cardiovascular risk, and (iii) patients received medication adjustments when indicated. The hypertension control rates at six months and at the last visit were recorded. Among the 1406 patients, about 75% had their baseline glucose and kidney function assessed. Nearly 30% (n = 425/1406) of patients were indicated for dual therapy but only 43% of them (n = 182/425) received this. During treatment, 28% (198/1406) required adjustments in medication but this was not done. The control of hypertension at six months after treatment initiation was 53% varying between 51% in community and 56% in large hospitals (p < .01). The hypertension control rate at last visit was 64% but varied between 59% in community hospitals and 71% in large hospitals (p < .01). Failure to adjust medication when required was associated with 30% decrease in the odds of hypertension control (OR 0.69, 95% CI 0. 50 to 0.90). Failure to comply with the treatment guidelines regarding adjustment of medication and lost to follow-up are possible target areas to improve hypertension control in Thailand.
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Angkurawaranon et al. (2021) conducted an observational in Hypertension (n=1,406). Adherence to hypertension treatment guidelines was evaluated on Hypertension control (OR 0.69, 95% CI 0.50-0.90). Failure to adjust hypertension medication when required was associated with a 30% decrease in the odds of hypertension control (OR 0.69; 95% CI 0.50-0.90).
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