Key result
An excessive fall in nocturnal blood pressure was significantly associated with a higher incidence of ischemic silent cerebrovascular lesions on MRI in elderly women.
Why the study?
Does an excessive fall in nocturnal blood pressure associate with silent cerebrovascular lesions in untreated middle-aged and elderly adults?
Population
151 untreated adults from northern Japan, including late middle age and elderly.
Comparison
Excessive fall in nocturnal blood pressure vs Normal or lesser fall in nocturnal blood pressure
Design
Cross-sectional
Authors
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May warrant nocturnal BP monitoring in elderly women; leaves open causality for silent lesions.
Cross-Sectional (n=151)
Does an excessive fall in nocturnal blood pressure associate with silent cerebrovascular lesions in untreated middle-aged and elderly adults?
An excessive fall in nocturnal blood pressure is associated with an increased burden of silent cerebrovascular lesions on MRI in elderly and late middle-aged women.
Watanabe et al. (1996) conducted a cross-sectional in Silent cerebrovascular lesions (n=151). Excessive fall in nocturnal blood pressure was evaluated on Incidence of silent cerebrovascular lesions on MRI (number of lacunar infarctions or extent of periventricular hyperintensity). An excessive fall in nocturnal blood pressure was significantly associated with a higher incidence of ischemic silent cerebrovascular lesions on MRI in elderly women.
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