Key result
Nondipper hypertensive patients had significantly higher median urinary albumin excretion (42 mg/24 h) compared to dippers (17.5 mg/24 h, P<.001) and normal subjects (8.6 mg/24 h).
Why the study?
Does a nondipper blood pressure pattern correlate with increased urinary albumin excretion in patients with essential hypertension?
Population
63 patients with essential hypertension and 21 healthy volunteers
Comparison
Nondipper blood pressure pattern vs Dipper blood pressure pattern and healthy…
Design
Cross-sectional
Authors
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Nondipper hypertension was associated with higher albuminuria; hypothesis-generating for renal risk stratification.
Observational (n=84)
Does a nondipper blood pressure pattern correlate with increased urinary albumin excretion in patients with essential hypertension?
Absolute Event Rate: 42% vs 17.5%
p-value: p=< .001
Hypertensive patients with a nondipper blood pressure pattern have significantly higher urinary albumin excretion compared to dippers, suggesting greater renal damage.
Bianchi et al. (1994) conducted an observational in Essential hypertension (n=84). Nondipper blood pressure pattern vs. Dipper blood pressure pattern was evaluated on Urinary albumin excretion (p=< .001). Nondipper hypertensive patients had significantly higher median urinary albumin excretion (42 mg/24 h) compared to dippers (17.5 mg/24 h, P<.001) and normal subjects (8.6 mg/24 h).
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