Why the study?
Do mechanical prosthetic mitral valves alter left ventricular flow dynamics and turbulence compared to physiological inflow in an in vitro model?
Population
In vitro silicone rubber, flexible left ventricle model
Comparison
Mechanical prosthetic valves mounted in mitral… vs Top hat inflow velocity profile
Design
Preclinical
Authors
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Bileaflet mitral prostheses may minimize LV turbulence versus monoleaflet designs; hypothesis-generating pending clinical validation.
Do mechanical prosthetic mitral valves alter left ventricular flow dynamics and turbulence compared to physiological inflow in an in vitro model?
In vitro modeling demonstrates that bileaflet mechanical mitral valves better preserve physiological left ventricular flow dynamics and generate less turbulence than monoleaflet valves.
Querzoli et al. (2010) studied this question.
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