Why the study?
Does the orientation of a tilting prosthetic mitral valve affect left ventricular blood flow and turbulence in an in vivo sheep model?
Population
11 sheep with preserved mitral subvalvular apparatus
Comparison
Implantation of a Medtronic Hall tilting valve… vs Preoperative ventricular blood flow and…
Design
Preclinical
Authors
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Anatomical mitral prosthesis orientation may preserve physiological LV flow; leaves open translation to human outcomes.
Does the orientation of a tilting prosthetic mitral valve affect left ventricular blood flow and turbulence in an in vivo sheep model?
Anatomical orientation of tilting disc mitral valve prostheses is crucial to maintain physiological left ventricular hemodynamics and minimize apical turbulence.
Mächler et al. (2007) studied this question.
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